I-Adenosine 5'-monophosphate | 61-19-8

I-Adenosine 5'-monophosphate (AMP) iyinucleotide eyakhiwe i-adenine, i-ribose, neqembu elilodwa le-phosphate.

Isakhiwo Samakhemikhali: I-AMP isuselwa ku-nucleoside adenosine, lapho i-adenine ixhunywe ku-ribose, futhi iqembu le-phosphate elengeziwe lixhunywe ku-5' carbon ye-ribose ngebhondi ye-phosphoester.

Indima Yebhayoloji: I-AMP iyingxenye ebalulekile yama-nucleic acid, esebenza njenge-monomer ekwakhiweni kwama-molecule e-RNA. Ku-RNA, i-AMP ifakwa ochungechungeni lwe-polymer ngamabhondi e-phosphodiester, yakhe umgogodla we-RNA strand.

I-Energy Metabolism: I-AMP nayo ibandakanyeka kumetabolism yamandla eselula. Isebenza njengesandulela se-adenosine diphosphate (ADP) kanye ne-adenosine triphosphate (ATP) ngokusebenzisa ukusabela kwe-phosphorylation okubangelwa ama-enzyme afana ne-adenylate kinase. I-ATP, ikakhulukazi, ingumthwali wamandla oyinhloko kumaseli, enikeza amandla ezinqubo ezihlukahlukene zamaselula.

I-Metabolic Regulation: I-AMP idlala indima ekulawuleni ibhalansi yamandla eselula. Amazinga e-Cellular AMP angashintshashintsha ekuphenduleni izinguquko ze-metabolic kanye nezidingo zamandla. Amazinga aphezulu e-AMP ahlobene ne-ATP angenza kusebenze izindlela zokuzwa amandla kumaselula, njenge-AMP-activated protein kinase (AMPK), elawula i-metabolism ukuze kugcinwe i-homeostasis yamandla.

Umthombo Wokudla: I-AMP ingatholakala emithonjeni yokudla, ikakhulukazi ekudleni okunothe ngama-nucleic acid, njengenyama, inhlanzi, nemifino.

I-Pharmacological Applications: I-AMP kanye nokuphuma kwayo kuye kwaphenywa ukuze kwenziwe izinhlelo zokwelapha ezingaba khona. Isibonelo, i-cAMP (cyclic AMP), okuphuma kokunye ku-AMP, isebenza njengesithunywa sesibili ezindleleni zokudlulisela isignali futhi iqondiswe imithi ehlukahlukene yokwelapha izimo ezifana nesifuba somoya, ukuphazamiseka kwenhliziyo, nokungalingani kwamahomoni.