I-Apple Root Extract 80% Phloridzin | 85251-63-4
Incazelo Yomkhiqizo:
Incazelo Yomkhiqizo:
I-Apple root bark extract, igama langempela elithi phloretin, igama langaphandle i-Dihydronaringenin, igama lamakhemikhali e-phloretin: 3-(4-hydroxyphenyl) -1-(2, 4, 6-trihydroxyphenyl) -1-propanone.
I-Phloretin iwuhlobo olusha lwe-ejenti yemvelo yokwenza isikhumba sibe mhlophe esanda kucwaningwa futhi yathuthukiswa phesheya. Isatshalaliswa kakhulu emakhasini nasezimpandeni zegxolo lezithelo ezinamanzi njengama-apula namapheya.
Ukusebenza kanye neqhaza le-Apple Root Extract 80% Phloridzin:
I-Antioxidant, anti free radical effect Ucwaningo luye lwabonisa ukuthi i-phloretin ingavimbela umsebenzi wama-melanocyte futhi inomphumela okhanyayo ezinhlobonhlobo ze-pigmentation zesikhumba.
1)Inomphumela omuhle wokuvimbela ku-tyrosinase, futhi iyi-ejenti emhlophe ye-freckle ephephe kakhulu futhi ephumelelayo.
2)I-Phloretin inomphumela omuhle kakhulu wokuthambisa futhi ingamunca izikhathi ezingama-4-5 isisindo sayo emanzini.
3) I-Phloretin iyisithuthukisi sokungena kwe-transdermal esiphephe kakhulu nesisebenza ngempumelelo, esingakhuthaza ukumuncwa kanye nokusetshenziswa kwezinye izici zokusebenza kufomula, ukuze ibe nomthelela ongcono.
I-4) I-Phloretin inomphumela omuhle we-LOX we-inhibitory, ngakho-ke, i-phloretin nayo iyi-ejenti enhle yokulwa nokulahlekelwa izinwele.
Imiphumela elwa nokuvuvukala kanye ne-immunosuppressive Ucwaningo luye lwabonisa ukuthi ukuvela kokuvuvukala kuhlobene ne-NO, eyenziwa yi-catalyzed futhi ihlanganiswe yi-NO synthase, futhi i-NO ngokweqile ezimweni ze-pathological i-catalyzed yi-Inducible NO synthase.
Ngaphansi kwesenzo se-phloretin, akukho ukukhululwa kwama-macrophages ngaphansi kokugqugquzelwa kwe-lipopolysaccharide ne-IFN-γ yehla kakhulu; izinga le-phagocytosis lamaseli e-megalith nalo lehla kakhulu ngaphansi kwesenzo se-phloretin.
Ngakho-ke, i-phloretin inemiphumela engaba khona yokulwa nokuvuvukala. Ku-immunosuppression, i-phloretin iyi-inhibitor eyaziwayo yokuncintisana ye-sodium D-glucose cotransporter. Njengoba ingakhuphula i-fluidity ye-lipid bilayers kumaseli, ingabamba iqhaza ekwandiseni uhlobo nomsebenzi wezidakamizwa ezilethwa kulo lonke ulwelwesi esikhumbeni.
Anti-tumor kanye nemiphumela elwa nomdlavuzaγδAmaseli e-T angama-innate immune T cell akhona kakhulu kuma-mucosal kanye nezicubu ze-epithelial zesistimu yokugaya ukudla, uhlelo lokuphefumula, njll.
I-anti-tumor effect yayo, ngaphezu kwezinye izici zokusebenza ezifana neawuT cell, futhi ibona ama-antigen ngaphandle kokwethulwa kwe-molecule ye-MHC. , Ukuqashelwa okuqondile kwama-antigen amaprotheni nama-peptide, ama-antigen angewona ama-peptide, anomsebenzi wokukhishwa kwe-antigen kanye nokulawulwa kwamasosha omzimba ngokuthintana kwamaseli kanye nokukhishwa kwama-cytokines.