Cytidine | 65-46-3

I-Cytidine iyi-molecule ye-nucleoside eyakhiwe yi-nucleobase cytosine exhunywe ku-ribose kashukela. Ingenye yamabhulokhi wokwakha we-RNA (ribonucleic acid) futhi idlala indima ebalulekile kumetabolism yamaselula kanye nokuhlanganiswa kwe-nucleic acid.

Isakhiwo Sekhemikhali: I-Cytidine iqukethe i-pyrimidine nucleobase cytosine exhunywe ku-five-carbon sugar ribose nge-β-N1-glycosidic bond.

Indima Yebhayoloji: I-Cytidine iyingxenye eyisisekelo ye-RNA, lapho isebenza njengenye yama-nucleosides amane asetshenziswa ekwakhiweni kwemicu ye-RNA ngesikhathi sokuloba. Ngaphezu kwendima yayo ekuhlanganiseni kwe-RNA, i-cytidine iphinde ibambe iqhaza ezindleleni ezihlukahlukene ze-metabolic, okuhlanganisa i-biosynthesis ye-phospholipids kanye nokulawulwa kwe-gene expression.

I-Metabolism: Ngaphakathi kwamaseli, i-cytidine ingaba yi-phosphorylated ukuze yakhe i-cytidine monophosphate (CMP), i-cytidine diphosphate (CDP), ne-cytidine triphosphate (CTP), okuyizinto ezibalulekile eziphakathi ku-nucleic acid biosynthesis nezinye izinqubo ze-biochemical.

Imithombo Yokudla: I-Cytidine itholakala ngokwemvelo ekudleni okuningi, okuhlanganisa inyama, inhlanzi, imikhiqizo yobisi, neminye imifino. Ingabuye itholakale ngokudla ngendlela yama-nucleotide ane-cytidine nama-nucleic acid.

Amandla Okwelapha: I-Cytidine kanye nokuphuma kwayo kuye kwaphenywa ukuze kusetshenziswe izindlela zokwelapha ezingase zibe khona ezimweni ezihlukahlukene zezokwelapha, okuhlanganisa ukuphazamiseka kwemizwa, umdlavuza, kanye nezifo ezibangelwa amagciwane. Isibonelo, ama-analogues e-cytidine afana ne-cytarabine asetshenziswa ekwelapheni ngamakhemikhali ukwelapha izinhlobo ezithile ze-leukemia ne-lymphoma.