I-Gotu Kola Extract 40% Asiaticosides | 16830-15-2

Ukwethulwa kwe-Gotu Kola ekhipha ama-40% Asiaticosides:

I-Centella asiatica, utshani obomisiwe be-Centella asiatica, yaqoshwa okokuqala "ku-Shen Nong's Materia Medica" futhi yafakwa ohlwini njengebanga eliphakathi.

Inemiphumela yokususa ukushisa nokuswakama, ukukhipha ubuthi nokunciphisa ukuvuvukala. Ukwelashwa kwemihuzuko, izifo zesikhumba, njll.

Izithako eziyinhloko ezisebenzayo ku-Centella asiatica extract engasetshenziswa ezimonyoni i-asiatic acid, i-madecassic acid, i-madecassoside ne-madecassoside, i-madecassoside iyi-saponin ye-triterpenoid ye-Centella asiatica Ingenye yezithako ezisebenzayo ezinengxenye ephezulu kakhulu, ibalwa cishe ngama-30% ingqikithi ye-glycosides ye-Centella asiatica.

Ukusebenza kanye nendima ye-Gotu Kola ikhipha ama-40% e-Asiaticosides: 

I-antibacterial

I-Centella asiatica extract iqukethe i-asiatic acid ne-madecassolic acid, lawa ma-saponins asebenzayo azofaka i-cytoplasm kumaseli ezitshalo, lo msebenzi we-antibacterial ungavikela isitshalo ngokwaso ekuhlaselweni kwesikhunta nemvubelo, ucwaningo lubonisa ukuthi i-Centella asiatica

Ukukhishwa kunomphumela othile ovimbelayo ku-Pseudomonas aeruginosa, i-Staphylococcus aureus ne-Propionibacterium acnes.

I-anti-inflammatory

I-Centella asiatica ingqikithi ye-glycosides inemiphumela esobala yokulwa nokuvuvukala: inciphisa ukukhiqizwa kwabalamuli be-pro-inflammatory (L-1, MMP-1), ithuthukise futhi ilungise umsebenzi wokuvimbela isikhumba, ngaleyo ndlela ivimbele futhi ilungise ukungasebenzi kahle kwamasosha omzimba.

Ukupholisa amanxeba nezibazi

I-Madecassoside kanye ne-madecassoside yizithako ezisebenzayo ze-Centella asiatica ekwelapheni amanxeba okushisa okuphulukisa.

Bangakwazi ukukhuthaza i-collagen synthesis kanye ne-angiogenesis emzimbeni, ikhuthaze ukukhula kwe-granulation nezinye izindima ezibalulekile, ngakho-ke zizuzisa ukuphulukiswa kwesilonda.

Ngasikhathi sinye, i-asiaticoside inomphumela wokwanda kuma-epidermal keratinocyte namaseli e-vascular endothelial, futhi inomphumela ovimbelayo kuma-fibroblasts, ngaleyo ndlela ikhuthaze ukwakheka kwezicubu ze-granulation ekuqaleni kokuphola kwesilonda, futhi ivimbele ukwakheka kwezibazi ngasekupheleni kwesigaba. umphumela wokuphulukisa isilonda.

Anti-ukuguga

Ukukhishwa kwe-Centella asiatica kungakhuthaza ukuhlanganiswa kwe-collagen I no-III, kanye nokukhishwa kwe-mucopolysaccharides (njengokuhlanganiswa kwe-sodium hyaluronate), ukwandisa ukugcinwa kwamanzi esikhumbeni, kusebenze futhi kuvuselele amangqamuzana esikhumba, ukuthambisa, ukuthuthukisa nokuthuthukisa isikhumba. Iyacwebezela.

Ngakolunye uhlangothi, ukuhlolwa kokulandelana kwe-DNA kwathola ukuthi i-Centella asiatica extract iphinde isebenze izakhi zofuzo ze-fibroblast, ezingathuthukisa ubungqabavu bamaseli esikhumba, ukugcina ukunwebeka nokuqina kwesikhumba, kanye nokushwabana kobuso obushelelezi.

I-Antioxidant

I-Asiaticoside, i-madecassoic acid kanye ne-madecassoic acid yonke inemisebenzi esobala yokulwa ne-antioxidant.

Imiphumela yokuhlolwa kwezilwane ibonisa ukuthi i-madecassoside ingaheha i-superoxide dismutase yendawo, i-glutathione ne-peroxidase emanxebeni asekuqaleni kokuphola kwesilonda.

Amazinga e-antioxidant afana ne-catalase, i-VitChing, i-VitE akhuphuke kakhulu, futhi izinga lama-peroxides e-lipid esilondeni lancipha izikhathi ezingu-7.

Ukuba mhlophe

I-Asiaticoside ingavimbela umsebenzi we-tyrosinase ngendlela encike kumthamo, futhi i-4μg/ml i-asiaticoside ivimbela i-tyrosinase ngo-4%.