I-Hydrolyzed Collagen | 92113-31-0

Incazelo Yomkhiqizo:

Ngemuva kwe-enzymatic hydrolysis ye-collagen, ingaba yi-collagen eyi-hydrolyzed (i-Hydrolyzed Collagen, eyaziwa nangokuthi i-collagen peptide).

I-Collagen polypeptide iqukethe izinhlobo eziyi-19 zama-amino acid. I-Collagen (ebuye ibizwe ngokuthi i-collagen) iyiphrotheni yesakhiwo se-matrix engaphandle kweseli futhi iyingxenye eyinhloko ye-extracellular matrix (ECM), ibalwa cishe ku-85% wezinto eziqinile ze-collagen fibers.

I-Collagen iyiphrotheni etholakala yonke indawo emzimbeni wesilwane, ikakhulukazi kuzicubu ezixhumeneyo (ithambo, uqwanga, isikhumba, i-tendon, ukuqina, njll.) 6%.

Ezilwaneni eziningi zasolwandle, njengesikhumba senhlanzi, amaprotheni afinyelela ku-80%.

Umsebenzi we-Hydrolyzed collagen

I-Hydrolyzed Collagen isetshenziswa kakhulu kuzimonyo, inemisebenzi efana nokunqanda ukushwabana, ukwenza mhlophe, ukulungisa, ukuthambisa, ukuhlanza, nokwenza ngcono ukunwebeka kwesikhumba.

I-Hydrolyzed Collagen ingasetshenziswa emikhiqizweni yokunakekelwa komzimba, engenza amangqamuzana asebenze, ithuthukise ukusebenza kwamasosha omzimba, ivimbele ukuguga, ivimbele ukuguga kwesikhumba, inciphise isisindo, ithonise umzimba, ikhulise ibele, njalonjalo.

Indlela yokukhiqiza ye-Hydrolyzed Collagen

I-hydrolyzed collagen ikhishwa emathanjeni nasesikhumbeni sezilwane eziye zahlukaniswa ngokwezempilo, futhi amaminerali emathanjeni nasesikhumbeni akhishwa nge-acid-grade dilute acid. Ingulube noma inhlanzi) ngemva kokwelashwa nge-alkali noma nge-asidi, amanzi e-high-purity reverse osmosis asetshenziselwa ukukhipha amaprotheni e-macromolecular collagen ezingeni lokushisa elithile, bese ngenqubo ekhethekile ye-enzymatic hydrolysis, iketango le-macromolecular lisikwa ngempumelelo, futhi eliphelele kakhulu. ukugcinwa Amaqembu e-amino acid asebenzayo, futhi abe yi-collagen ene-hydrolyzed enesisindo samangqamuzana angama-2000-5000 Daltons.

Inqubo yokukhiqiza ifinyelela izinga eliphezulu kakhulu lomsebenzi webhayoloji nobumsulwa ngokuhlunga okuningi kanye nokususwa kwama-ion angcolile, futhi ngenqubo yesibili yokuvala inzalo okuhlanganisa izinga lokushisa eliphezulu elingu-140 °C ukuze kuqinisekiswe ukuthi okuqukethwe kwebhaktheriya kungaphansi kuka-100/g (leli zinga ama-microorganisms aphakeme kakhulu kune-1000/g yezinga le-EU), futhi afafazwe nge-granulation yesibili ekhethekile ukuze enze i-collagen powder encibilika kakhulu, egayeka ngokuphelele. Incibilika emanzini abandayo, igayeka kalula futhi imuncwe.

Izinzuzo ze-Hydrolyzed Collagen

(1) I-collagen ene-Hydrolyzed inokumuncwa okuhle kwamanzi:

Ukumuncwa kwamanzi yikhono lephrotheni lokumunca noma ukumunca amanzi. Ngemuva kwe-collagenase hydrolysis, i-collagen ye-hydrolyzed iyakhiwa, futhi inani elikhulu lamaqembu e-hydrophilic livezwa, okuholela ekwandeni okukhulu kokumuncwa kwamanzi.

(2) Ukuncibilika kwe-collagen e-hydrolyzed kuhle:

Ukuncibilika kwamanzi kweprotheni kuncike enanini lamaqembu a-ionzable kanye namaqembu e-hydrophilic ku-molecule yawo. I-hydrolysis ye-collagen ibangela ukuphuka kwamabhondi e-peptide, okuholela emaqenjini athile e-polar hydrophilic.

Ukwanda kwenani (njenge -COOH, -NH2, -OH) kunciphisa i-hydrophobicity yeprotheni, kwandisa ukuminyana kokushaja, kwandisa i-hydrophilicity, futhi kwandisa ukuncibilika kwamanzi.

(3) Amandla aphezulu wokugcina amanzi e-collagen e-hydrolyzed:

Amandla okugcina amanzi eprotheni athintwa ukugcwala kwamaprotheni, isisindo samangqamuzana, izinhlobo ze-ion, izici zemvelo, njll., futhi ngokuvamile kuvezwa izinga lensalela yamanzi.

Njengoba izinga le-collagen hydrolysis likhula, izinga lokugcinwa kwamanzi nalo likhuphuka kancane kancane.

(4) I-Chemotaxis ye-hydrolyzed collagen kuma-fibroblasts:

I-Prolyl-hydroxyproline izovela egazini le-peripheral ngemva kokungenisa komuntu i-hydrolyzed collagen, futhi i-prolyl-hydroxyproline ingase ivuselele isikhumba I-Fibroblasts ikhule, ikhulise inani le-fibroblasts efudukayo esikhumbeni, ithuthukise ukuguqulwa kwamangqamuzana e-epidermal, isheshise ukugeleza kwamanzi esikhumbeni. ungqimba wesikhumba, uthuthukise ikhono lesikhumba lokuthambisa, futhi uvimbele ukwakheka kwemibimbi ejulile.

Ukusetshenziswa kwe-Hydrolyzed Collagen ku-Cosmetics

I-Collagen i-enzymatic hydrolyzed ukuze yakhe i-collagen e-hydrolyzed, futhi ukwakheka kwayo kwamangqamuzana nesisindo se-molecule kuyashintshwa, okuholela ekushintsheni kwezakhiwo zayo zokusebenza njengokumuncwa kwamanzi, ukuncibilika, nokugcinwa kwamanzi.

I-chemotaxis ye-hydrolyzed collagen kuya ku-fibroblasts ikhuthaza ukukhula kwe-fibroblasts esikhumbeni, ikhuphula kakhulu ukuminyana kwe-fibroblast, i-collagen fiber diameter kanye nokuminyana, kanye nephesenti le-dermatan sulfate ku-decorin, okwenza isikhumba siqine ngomshini. ukuqina, amandla okuthambisa aqinile, kanye nemibimbi yesikhumba emihle nejulile.