Iopamidol|60166-93-0

I-Iopamidol, eyaziwa nangokuthi i-iodopeptidol, iodopentanol, iopamidol, iopamidol, iodobidol, iopamisone, iyi-ejenti engafani ye-ionic encibilika emanzini, okuyisidakamizwa sokuxilongwa kwesithombe. Ukwakheka kwamakhemikhali ayo I-amide compounds ye-triiodoisophthalic acid derivatives inobuthi obuphansi ezindongeni zemithambo yegazi nezinzwa, ukubekezelelana okuhle kwendawo kanye nesistimu, ukucindezela okuphansi kwe-osmotic, i-viscosity ephansi, umehluko omuhle, umjovo ozinzile, kanye ne-deiodination encane kakhulu ku-vivo. I-Myelography kanye neziguli ezinezici eziyingozi kakhulu zokusabela ngokungafani. Ngemuva komjovo we-intravascular we-iopamidol, ikhishwa ikakhulukazi ezinso. I-T1/2 iyahlukahluka ngokusebenza kwezinso, ngokuvamile amahora angu-2 kuya kwangu-4, futhi ikhishwa ikakhulukazi ngendlela yokuqala ngomchamo, i-90% kuya ku-95% ikhishwa emahoreni angu-7 kuya kwangu-8, futhi cishe i-100% ikhishwa emahoreni angu-20. Ku-vivo, i-iopamidol ayigayelwanga i-metabolism, ayibophi amaprotheni e-plasma, futhi ayiphazamisi ama-isoenzymes. Ngenxa yokuqukethwe okuphezulu kwe-iodine, lo mkhiqizo unciphisa ama-X-reyi ukuze ufinyelele injongo yokuqhathanisa izithombe, futhi ufanele ukugqama kwe-X ray ngomjovo we-intravascular. I-Iopamidol isetshenziselwa ukwelapha i-angiography ehlukahlukene, njenge-cerebral arteriography. I-angiography yenhliziyo ihlanganisa imithambo yenhliziyo, imithambo yesifuba neyesisu, imithambo eseceleni, imithambo, kanye ne-digital subtraction angiography. Futhi i-urinary tract, amalunga, i-fistula, intambo yomgogodla, umthombo kanye ne-ventricle, i-visceral arteriography ekhethiwe. Ukuskena okuthuthukisiwe ekuhlolweni kwe-CT.