I-Magnolia Cortex Extract 2% Honokiol | 35354-74-6

I-Magnolia officinalis extract (igama lesiNgisi: Magnolia officinalis PE ), izithako ezisebenzayo: kanye ne-magnolol, i-magnolol, i-magnolol ingqikithi ye-phenol. Umthombo wezitshalo: Isithako esisebenzayo kumsebenzi wokulwa namagciwane egxolweni le-Magnolia officinalis Rehder et Wilson, umuthi wendabuko waseShayina.

Lo mkhiqizo uyi-off-white powder crystal. Incibilika ku-benzene, i-ether, i-chloroform, i-acetone, ayincibiliki emanzini, incibilika kalula kusisombululo se-alkali esincibilikayo ukuze kutholwe usawoti we-sodium. Iqembu le-phenolic hydroxyl kulula ukuba lifakwe i-oxidized, kuyilapho iqembu le-Allyl kulula ukubhekana nokusabela kokwengezwa.

Inomphumela okhethekile, ohlala isikhathi eside wokuphumula kwemisipha kanye nomphumela onamandla we-antibacterial, ongavimbela ukuhlangana kweplatelet.

Ngokomtholampilo, isetshenziswa ikakhulukazi njengesidakamizwa esilwa namagciwane kanye ne-antifungal. Lo mkhiqizo kufanele uvalwe kude nokukhanya futhi ugcinwe endaweni eyomile, epholile futhi enomoya omuhle.

Ukusebenza kanye nendima ye-Magnolia Cortex Extract 2% Honokiol: 

I-anti-inflammatory

Ekuphenduleni kokuvuvukala, i-cell membrane phospholipids ikhulula i-arachidonic acid (AA) ngaphansi kwesenzo se-phospholipase A2.

Kunezindlela ezimbili ze-metabolic ye-AA, eyodwa ukukhiqiza i-prostaglandin nama-thromboxanes ngesenzo se-cyclooxygenase (COX), kanti enye iwukukhiqiza ama-prostaglandin nama-thromboxanes ngesenzo se-cyclooxygenase (COX). Isenzo se-lipoxygenase (LO) sikhiqiza i-leukotrienes (LT).

I-Honokiol ekugxilweni okuphezulu ivimbele umsebenzi we-COX kumaseli aphazamisekile, ngenkathi ivimbela indlela ye-LO metabolic. Ngakho-ke, i-honokiol iyi-dual inhibitor ye-COX ne-LO.

Umphumela wokulwa nokuvuvukala kwe-honokiol ungase uhlotshaniswe nokuvinjwa kwayo izindlela ezimbili ze-metabolic ze-AA. Ngaphezu kwalokho, i-honokiol ingavimbela ukukhululwa kwama-enzyme e-lysosomal, inciphise ukungena kwezindonga ze-capillary ezungeze indawo yokuvuvukala, futhi ivimbele ukufuduka kwe-leukocyte kanye nokwanda kwezicubu ze-fibrous.

I-Antioxidant

I-Magnolol ne-Honokiol inemiphumela yamahhala yokulahla i-radical, engasusa i-parahydroxyl radicals ne-hydrogen peroxide.

Ngesikhathi esifanayo, ingavikela umsebenzi wama-enzyme eketango lokuphefumula le-mitochondrial ngokumelene nengcindezi ye-peroxidative eyenziwe yi-NADPH, iphikisane ne-oxidative hemolysis yamangqamuzana egazi abomvu, futhi ivimbele i-lipid peroxidation.

Izifundo ezimbalwa ze-in vitro kanye ne-vivo zihlole umsebenzi we-antioxidant we-Magnolia officinalis extract, enamandla izikhathi eziyi-1000 kune-alpha-tocopherol.