I-Microcrystalline Cellulose (MCC) | 9004-34-6
Incazelo Yemikhiqizo
I-Microcrystalline cellulose igama le-pulp yokhuni elicwengekile futhi isetshenziswa njenge-texturizer, i-anti-caking agent, indawo yamafutha, i-emulsifier, i-extender, kanye ne-bulking ejenti ekukhiqizeni ukudla.Ifomu elivame kakhulu lisetshenziselwa izithasiselo zamavithamini noma amaphilisi. Ibuye isetshenziswe ekuhlolweni kwama-plaque ukubala amagciwane, njengenye indlela ye-carboxymethylcellulose.Ngezindlela eziningi, i-cellulose yenza i-excipient efanelekile. I-polymer eyenzeka ngokwemvelo, yakhiwe amayunithi e-glucose axhunywe nge-1-4 beta glycosidic bond. Lawa maketango e-cellulose aqondile ahlanganiswe ndawonye njenge-microfibril ehlanganiswe ndawonye ezindongeni zeseli lesitshalo. I-microfibril ngayinye ibonisa izinga eliphezulu lokubopha kwangaphakathi kwezinhlangothi ezintathu okuholela esakhiweni sekristalu esingancibiliki emanzini futhi simelana nama-reagents. Kukhona, nokho, izingxenye ezibuthakathaka ngokuqhathaniswa ze-microfibril ezinokuhlangana okubuthakathaka kwangaphakathi. Lezi zibizwa ngokuthi izifunda ze-amorphous kodwa zibizwa ngokunembe kakhulu ngokuthi i-dislocation kusukela i-microfibril iqukethe isakhiwo sesigaba esisodwa. Isifunda se-crystalline sihlukaniswe ukukhiqiza i-microcrystalline cellulose.
Ukucaciswa
| ITEM | IZINGA |
| Ukubukeka | Impushana emhlophe noma cishe emhlophe engenaphunga |
| Usayizi wezinhlayiya | U-98% uphase i-120 mesh |
| I-Assay (njenge-α-cellulose, isisekelo esomile) | ≥97% |
| Into encibilikayo emanzini | ≤ 0.24% |
| Umlotha one-sulphate | ≤ 0.5% |
| i-pH (isixazululo esingu-10%) | 5.0- 7.5 |
| Ukulahlekelwa ekomisweni | ≤ 7% |
| Isitashi | Okubi |
| Amaqembu e-Carboxyl | ≤ 1% |
| Ukuhola | ≤ 5 mg/kg |
| I-Arsenic | ≤ 3 mg/kg |
| I-Mercury | ≤ 1 mg/kg |
| I-Cadmium | ≤ 1 mg/kg |
| Izinsimbi ezisindayo (njenge-Pb) | ≤ 10 mg/kg |
| Inani lepuleti eliphelele | ≤ 1000 cfu/g |
| Imvubelo nesikhunta | ≤ 100 cfu/g |
| E. coli/ 5g | Okubi |
| Salmonella / 10g | Okubi |
