I-Polygonum Multiflorum Extract

I-Polygonum multiflora (Igama lesayensi: i-Fallopia multiflora (Thunb.) Harald.), eyaziwa nangokuthi i-Polygonum multiflora, i-Violet vine, i-Night vine njalonjalo.

Iwumvini ohlangene ongapheli womndeni wePolygonum Polygonaceae, iPolygonum multiflorum, enezimpande eziwugqinsi, oblong, onsundu ngokumnyama. Imila ezigodini nasezihlahleni, ngaphansi kwamahlathi asemagqumeni, nasemifantwini yamatshe ngasemseleni.

Ikhiqizwe eningizimu yeShaanxi, eningizimu yeGansu, eMpumalanga yeChina, eCentral China, eNingizimu China, eSichuan, eYunnan naseGuizhou.

Izimpande zayo ezinama-tuberous zisetshenziswa njengomuthi, ongadambisa imizwa, ondle igazi, enze izibambiso zisebenze, akhiphe ubuthi (ukusika umalaleveva), futhi aqede ama-carbuncles.

Ukusebenza kanye nendima ye-Polygonum Multiflorum Extract: 

Umphumela wokuguga

Izilwane ezikhulile ziqoqa inani elikhulu lemikhiqizo ye-lipid peroxidation, ehambisana nokuncipha komsebenzi we-superoxide dismutase.

Imiphumela yokuhlola ibonisa ukuthi i-Polygonum multiflorum inganciphisa kakhulu okuqukethwe kwe-malondialdehyde ebuchosheni kanye nezicubu zesibindi zamagundane asebekhulile, ikhulise okuqukethwe kwe-monoamine transmitters ebuchosheni, ithuthukise umsebenzi we-SOD, futhi ingavimbela ngokuphawulekayo ukuvezwa kwe-monoamine oxidase. -B ebuchosheni nasesibindini samagundane asebekhulile.

Ukwenza kusebenze, ngaleyo ndlela kuqedwe ukulimala kwama-radicals mahhala emzimbeni, kubambezeleke ukuvela kokuguga nezifo.

Imiphumela kumasosha omzimba

I-Immunology ikholelwa ukuthi ukwehla komsebenzi wokuzivikela komzimba kuhlobene eduze nokuguga komzimba. I-thymus iyisitho esiyinhloko samasosha omzimba futhi ingagcina ngempumelelo umsebenzi wokuzivikela omzimba. I-Polygonum multiflorum ingabambezela ukuwohloka kwe-thymus ngokuguga, okungase kube yindlela ebalulekile yokubambezela ukuguga nokuthuthukisa amasosha omzimba.

Ukunciphisa i-lipids yegazi kanye ne-anti-atherosclerosis

I-Polygonum multiflorum ingathuthukisa ikhono lomzimba lokusebenza futhi isuse i-cholesterol, inciphise amazinga e-lipid egazini, ibambezele ukukhula kwe-atherosclerosis.

Indlela yomphumela wokwehlisa i-lipid we-Polygonum multiflorum ayikacaciswa, futhi ingaqedwa ngenye yalezi zindlela ezilandelayo noma ngokubambisana:

(1) Umphumela we-cathartic we-anthraquinones usheshisa i-metabolism yobuthi emzimbeni futhi ubuyisele indlela yokugaya amafutha esibindi;

(2) Ithinta ngempumelelo imisebenzi ye-3-hydroxy-3-methylglutaryl-CoA reductase kanye ne-Ta-hydroxylase esibindini, ivimbele ukuhlanganiswa kwe-cholesterol engapheli, ikhuthaze ukuguqulwa kwe-cholesterol ibe yi-bile acid, futhi ivimbele ukukhululwa kwe-bile acids. kusuka emathunjini. i-reabsorption yepheshana, ithuthukisa ukuphuma kwe-bile acid emathunjini;

(3) Kuhlobene nokuyenga i-microsomal carboxylesterase yesibindi, ukukhuthaza inqubo ye-hydrolysis emzimbeni, kanye nokusheshisa ukuphuma kobuthi emzimbeni.

Ukuvikelwa kwe-myocardial

Ucwaningo luthole ukuthi i-Polygonum multiflorum extract inomphumela wokuvimbela ekulimazeni kwe-myocardial ischemia-reperfusion ezinjeni.

Ukuvikelwa kwesibindi

I-stilbene glycosides equkethwe ku-Polygonum multiflorum inomphumela ophikisayo omkhulu ekulimaleni okunamafutha kwesibindi nokusebenza kwesibindi kumagundane abangelwa uwoyela wommbila we-peroxidized, ukwandisa okuqukethwe kwe-lipid peroxidation esibindini, futhi andise i-serum alanine aminotransferase kanye ne-aspartate aminotransferase. Ama-acids angenawo amafutha e-serum kanye ne-hepatic lipid peroxidation ingehla kakhulu.

Imiphumela ye-Neuroprotective

I-Polygonum multiflorum extract ingavimbela ukukhiqizwa kwe-interleukin ne-nitric oxide ngendlela encike ekugxiliseni, ngaleyo ndlela ivikele i-neuronal.

Umphumela we-antibacterial

Eminye imisebenzi

I-Polygonum multiflorum inemiphumela efana ne-adrenocortical hormone, futhi okuphuma kuyo i-anthraquinone equkethwe kuyo kungakhuthaza i-peristalsis yamathumbu futhi ibe nomthelela omncane wokulalisa.