I-Cnidium Fruit Extract | 484-12-8

Incazelo Yomkhiqizo:

I-Cnidium, eyaziwa nangokuthi i-fennel yasendle, imbewu yekarothi yasendle, irayisi lenyoka, i-chestnut yenyoka, njll., isithelo esomile esivuthiwe se-Cnidium monnieri, isitshalo se-Umbelliferae Apiaceae.

I-Cnidium isitshalo saminyaka yonke. Ithanda indawo efudumele nenomswakama, ayiwesabi amakhaza anamandla nesomiso, futhi ikwazi ukuzivumelanisa nezimo. Isatshalaliswa eMpumalanga China, Emaphakathi naseNingizimu China nakwezinye izifunda.

Ukusebenza kanye nendima ye-Cnidium Fruit Extract: 

I-Osthole inomphumela ovimbelayo ku-Staphylococcus aureus, i-Pseudomonas aeruginosa kanye ne-Escherichia coli, futhi inganciphisa futhi i-pathogenicity ye-Staphylococcus aureus strains residual.

Ingasetshenziswa ngokuhambisana ne-matrine, njll. ukwelapha i-trichomonas vaginitis, i-eczema, i-psoriasis, njll.

I-Anti-inflammatory: 

I-Osthole inomphumela ovimbelayo ku-Staphylococcus aureus futhi inomphumela omuhle ekuvuvukeni kwamagciwane. I-Osthole ihlanganiswe ne-baicalin ingakwazi ukwelapha i-pneumonia ebangelwa yi-Staphylococcus aureus.

I-Anti-Cancer:

OI-sthole ingavimbela ukukhula kwe-tumor kumamodeli omdlavuza wesibindi segundane, yenze i-apoptosis yamangqamuzana omdlavuza wesibindi ngokusebenzisa izinhloso eziningi nezindlela eziningi, futhi ithuthukise impendulo ye-anti-tumor immune yamagundane omdlavuza wesibindi; I-osthole ingaphinde ibulale amaseli omdlavuza we-Pharyngeal wamakhala, amangqamuzana omdlavuza wamaphaphu kanye namaseli omdlavuza womlomo wesibeletho anemiphumela evimbela ukukhula kwamaseli ahlukahlukene wesimila. Ingasetshenziswa ukusiza ukulwa nomdlavuza.

I-Anti-osteoporosis:

I-Osthole ingakhuthaza kakhulu ukwanda nokuhlukaniswa kwamaseli we-mesenchymal stem cell kanye ne-osteoblasts yomnkantsha, futhi ngesikhathi esifanayo ikhulise kakhulu amazinga e-osteocalcin ne-alkaline phosphatase, ngaleyo ndlela ikhuthaze ukwakheka kwamathambo, ukwandisa okuqukethwe kwamaminerali amathambo namandla Amathambo. I-Osthole ikhuthaza ukwanda nokuhlukaniswa kwama-osteoblasts maqondana nokugxila, futhi ukugxila okuhle kakhulu kuphakathi kuka-5 * 10-5M-5 * 10-4M.

Ngaphezu kwalokho, inhlanganisela ye-osthole ne-puerarin ingakwazi ukwelapha i-bone dysplasia kanye ne-osteoporosis.

Imiphumela ohlelweni lwe-endocrine:

I-Osthole ingakhuthaza ukuhlanganiswa nokukhishwa kwe-androgen kumaseli e-Leydig ngokulawula ukubhaliswa kofuzo kwama-enzyme ahlobene kanye ne-cell membrane kanye nama-receptor ahlobene ne-cytoplasm ohlelweni lwe-androgen synthesis kumaseli we-Leydig kumagundane;

Ingakhuphula okuqukethwe kwe-testosterone, i-follicle-stimulating hormone kanye ne-luteinizing hormone ku-serum, futhi inemiphumela efana ne-androgen-like ne-gonadotropin; kanye ne-osthole ku-40-80μg/mL ingakwazi ukukhulula ngokuphumelelayo ukucindezeleka kwe-oxidative okubangelwa i-H2O2 kuzicubu ze-ovarian. Khuthaza ukulimala, uvikele ukusebenza kwezicubu ze-ovarian, futhi uthuthukise umthamo we-antioxidant wezicubu ze-ovarian.

Okuqukethwe okuphansi kwe-osthole kungasetshenziswa njengesibulala-zinambuzane esithathwe ezitshalweni, isivikelo sokugcina okusanhlamvu, njll. I-1% ye-emulsion yamanzi e-osthole inemiphumela ekhethekile kumakhabe, ama-strawberry kanye ne-flower powdery mildew (ukusebenza kahle kokuvimbela cishe ku-95%), futhi inomphumela ohlangene ku-downy mildew yemifino kanye nama-aphid.

Uma kuqhathaniswa nezinye izibulala-zinambuzane ze-botanical, i-osthole inezinzuzo zokusebenza kahle kakhulu kanye nobuthi obuphansi.