Flubendazole |31430-15-6
Ukucaciswa komkhiqizo:
I-Flubenzimidazole iyinambuzane yokwenziwa ye-benzimidazole engavimbela ukumuncwa kwe-nematode kanye nokuhlanganisa ama-microtubules e-intracellular.
Ingase ibe nokuhlobana okuqinile ne-tubulin (i-dimer subunit protein ye-microtubules) futhi ivimbele ama-microtubules ekubeni abe yi-polymerizing kumaseli okumuncwa (okungukuthi amaseli okumunca kumaseli amathumbu e-nematode).Ingaqinisekiswa ngokunyamalala kwama-microtubules (ama-cytoplasmic) amahle kanye nokuqoqwa kwezinhlayiya eziyimfihlo ku-cytoplasm ngenxa yokudluliselwa okuvinjiwe.
Ngenxa yalokho, i-membrane ye-membrane enamathela iba mncane, futhi ikhono lokugaya nokumunca imisoco liyancipha.Ngenxa yokunqwabelana kwezinto ezifihliwe (ama-hydrolases nama-proteolytic enzymes), amaseli athola i-lysis kanye nokuwohloka, ekugcineni okuholela ekufeni kwe-parasite.
Isicelo:
I-Flubenzimidazole iyisidakamizwa esixosha izinambuzane esine-spectrum esikwazi ukwelapha izimuncagazi ezinjeni, njengezikelemu zamathumbu, ama-hookworms, nezikelemu;Ngesikhathi esifanayo, ingakwazi futhi ukwelapha ama-parasite amaningi amathumbu ezingulube nasezinkukhuni, njenge-Ascaris suum, i-Hyostrongylus rubidus, i-Oesophagostomum dentatum, i-Trichuris suis, i-Metastrongylus apri, njll.
I-Flubenzimidazole ayikwazi ukubulala abantu abadala kuphela kodwa namaqanda.
Iphakheji: 25 kgs/isikhwama noma njengoba ucela.
Isitoreji: Gcina endaweni engenawo umoya, eyomile.
Izinga eliphezulu: Izinga lamazwe ngamazwe.
