I-Topiroxostat|577778-58-6

I-Topicastat inomphumela wokuncintisana wokuvimbela ku-xanthine oxidoreductase, ngaleyo ndlela ivimbele ukukhiqizwa kwe-uric acid. Ayinawo umthelela ovimbelayo kwamanye ama-enzyme e-pyrimidine purine metabolizing, kodwa ngokukhethayo ivimbela umphumela we-Chemicalbook ku-xanthine oxidoreductase. I-Topicastat inomphumela obalulekile wokuvimbela kokubili i-XOR ene-oxidized futhi encishisiwe, ngakho umphumela wayo wokwehlisa i-uric acid unamandla kakhulu futhi uhlala isikhathi eside, ngakho-ke lo mkhiqizo ungasetshenziswa ekwelapheni i-hyperuricemia engapheli ku-gout.