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I-Topicastat inomphumela wokuncintisana wokuvimbela ku-xanthine oxidoreductase, ngaleyo ndlela ivimbele ukukhiqizwa kwe-uric acid.Ayinawo umthelela ovimbelayo kwamanye ama-enzyme e-pyrimidine purine metabolizing, kodwa ngokukhethayo ivimbela umphumela we-Chemicalbook ku-xanthine oxidoreductase.I-Topicastat inomphumela obalulekile wokuvimbela kokubili i-XOR ene-oxidized futhi encishisiwe, ngakho umphumela wayo wokwehlisa i-uric acid unamandla kakhulu futhi uhlala isikhathi eside, ngakho-ke lo mkhiqizo ungasetshenziswa ekwelapheni i-hyperuricemia engapheli ku-gout.