L-Tyrosine | 60-18-4
Incazelo Yemikhiqizo
I-Tyrosine (efushanisiwe ngokuthi i-Tyr noma i-Y) noma i-4-hydroxyphenylalanine, ingenye yama-amino acid angu-22 asetshenziswa amaseli ukuze ahlanganise amaprotheni. Ihlanganisa i-UAC ne-UAU. Kuyi-amino acid engabalulekile eneqembu le-polar side. Igama elithi "tyrosine" lisuselwa kwelesiGreki elithi tyros, okusho ushizi, njengoba latholwa okokuqala ngo-1846 ngusokhemisi waseJalimane uJustus von Liebig ku-proteincasein evela kushizi. Ibizwa ngokuthi i-tyrosyl uma ibizwa ngokuthi i-groupor side chain.yrosine iyisandulela sama-neurotransmitters futhi inyusa amazinga e-plasmaneurotransmitter (ikakhulukazi i-DOPAM ne-norepinephrine) kodwa iyancipha uma kukhona umthelela kumizwa. Umphumela wesimo sengqondo ubonakala kakhulu kubantu abangaphansi kwezimo ezicindezelayo.
Ngaphandle kokuba yi-proteinogenic aminoacid, i-tyrosine inendima ekhethekile ngenxa yokusebenza kwe-phenol. Ivela kumaprotheni ayingxenye yezinqubo zokudlulisa isignali. Isebenza njengesamukeli samaqembu e-phosphate adluliswa ngendlela yama-proteinkinase (okubizwa ngokuthi i-receptor tyrosine kinases). I-phosphorylation ye-hydroxylgroup ishintsha umsebenzi wephrotheni eqondiwe.
Izinsalela ze-tyrosine nazo zidlala indima ebalulekile ku-photosynthesis. Kuma-chloroplast (i-photosystem II), isebenza njengomnikeli we-anelectron ekunciphiseni i-chlorophyll ene-oxidized. Kule nqubo, idlula i-deprotonation ye-phenolic OH-group yayo. Le radical kamuva yehliswa ku-photosystem II ngamaqoqo amane ayisisekelo e-manganese.
Ucwaningo oluningi luye lwathola ukuthi i-tyrosine ingaba wusizo ezimweni zokucindezeleka, amakhaza, ukukhathala, ukulahlekelwa othandekayo njengokufa noma isehlukaniso, umsebenzi omude nokuntula ubuthongo, ngokunciphisa amazinga e-hormone yokucindezeleka, ukunciphisa ukulahlekelwa kwesisindo okubangelwa ukucindezeleka okubonakalayo. ukuhlolwa kwezilwane, ukuthuthukiswa kokusebenza kwengqondo nokusebenza ngokomzimba okubonwa ekuhlolweni kwabantu; kodwa-ke, ngenxa yokuthi i-tyrosine hydroxylase iyi-enzyme enciphisa izinga, imiphumela ayibalulekile kakhulu kunaleyo ye-L-DOPA.
I-Tyrosine ibonakala ingenawo umthelela obalulekile kumizwa, ingqondo noma ukusebenza komzimba ezimweni ezivamile. Umthamo wansuku zonke wokuhlolwa komtholampilo osekelwa ezincwadini cishe u-100 mg/kg kumuntu omdala, okulingana namagremu angu-6.8 ku-150 lbs. Umthamo ojwayelekile ufinyelela ku-500-1500 mg ngosuku (umthamo ophakanyiswa abakhiqizi abaningi; imvamisa ulingana namakhepsuli angu-1-3 e-tyrosine emsulwa). Akunconyelwe ukweqa i-12000 mg (12 g) ngosuku.
Ukucaciswa
| Izinto | Okujwayelekile | Imiphumela yokuhlolwa |
| Ukuzungezisa Okuthile[a]ᴅ²⁰ | -9.8°kuya-11.2° | -10.4° |
| I-Chloride(CI) | Hhayi ngaphezu kuka-0.05% | ＜0.05% |
| I-Sulfate(SO₄) | Hhayi ngaphezu kuka-0.04% | ＜0.04% |
| Insimbi(Fe） | Hhayi ngaphezu kuka-0.003% | ＜0.003% |
| Izinsimbi ezinzima | Hhayi ngaphezu kuka-0.00015% | ＜0.00015% |
| Ukulahlekelwa ekomisweni | Hhayi ngaphezu kuka-0.3% | ＜0.3% |
| Izinsalela Ekushiseni | Hhayi ngaphezu kuka-0.4% | ＜0.4% |
| Isivivinyo | 98.5%-101.5% | 99.3% |
| Isiphetho | Vumelanisa ne-USP32 ejwayelekile | |
