Melitha |20449-79-0

I-Melittin iwubuthi be-peptide obutholakala ebuhlungwini bezinyosi, ikakhulukazi ebuhlungwini bezinyosi (Apis mellifera).Ingenye yezingxenye eziyinhloko ze-bee venom futhi inomthelela emiphumeleni yokuvuvukala kanye nezinhlungu ezihambisana nezinyosi zezinyosi.I-Melittin iyi-peptide encane, eqondile equkethe ama-amino acid angama-26.

Izici ezibalulekile ze-melittin zifaka:

Isakhiwo: I-Melittin inesakhiwo se-amphipathic, okusho ukuthi inokubili izifunda ze-hydrophobic (ezixosha amanzi) kanye ne-hydrophilic (eheha amanzi).Lesi sakhiwo sivumela i-melittin ukuthi ihlanganyele futhi iphazamise ulwelwesi lwamaseli.

Indlela Yesenzo: I-Melittin yenza imiphumela yayo ngokusebenzisana nolwelwesi lwamaseli.Ingakha ama-pores ku-lipid bilayer ye-membrane yeseli, okuholela ekwandeni kokungena.Lokhu kuphazamiseka kolwelwesi lwamangqamuzana kungabangela i-cell lysis kanye nokukhululwa kokuqukethwe kwamaselula.

I-Inflammatory Response: Lapho inyosi ihlaba, i-melittin ijovwa esikhumbeni sesisulu kanye nezinye izakhi zobuhlungu.I-Melittin inomthelela ebuhlungu, ukuvuvukala, kanye nokubabomvu okuhambisana nezinyosi ngokufaka impendulo yokuvuvukala.

Izakhiwo Ze-Antimicrobial: I-Melittin iphinde ibonise izakhiwo ze-antimicrobial.Icutshungulwe ngekhono layo lokuphazamisa ulwelwesi lwamabhaktheriya, amagciwane, kanye nesikhunta, okuyenza ibe isihloko esithakaselwayo ngezinhlelo zokwelapha ezingase zibe khona, njengokwakhiwa kwama-antimicrobial agents.

Izicelo Zokwelapha Ezingenzeka: Naphezu kwendima yayo ebuhlungu nokuvuvukala okubangelwa izinyosi zezinyosi, i-melittin iye yaphenywa ngokusetshenziswa kwayo kokwelapha okungenzeka.Ucwaningo luye lwahlola izici zalo zokulwa nokuvuvukala kanye nezokulwa nomdlavuza, kanye namandla ayo ezinhlelweni zokulethwa kwezidakamizwa.

Iphakheji:25KG/BAG noma njengoba ucela.

Isitoreji:Gcina endaweni engenawo umoya, neyomile.

IsikhuluOkujwayelekile:Izinga lamazwe ngamazwe.